The following films received multiple nominations.
- 9 nominations: Avatar and The Hurt Locker
- 8 nominations: Inglourious Basterds
- 6 nominations: Precious: Based on the Novel “Push” by Sapphire and Up in the Air
- 5 nominations: Up
- 4 nominations: District 9, Nine and Star Trek
- 3 nominations: An Education, Crazy Heart, The Princess and the Frog and The Young Victoria
- 2 nominations: A Serious Man, The Blind Side, Fantastic Mr. Fox, Invictus, The Imaginarium of Dr. Parnassus, The Last Station, The Messenger, Sherlock Holmes and The White Ribbon
Best Picture – The Hurt Locker
Best Director – Kathryn Bigelow – The Hurt Locker
Best Actor – Jeff Bridges – Crazy Heart
Best Actress – Sandra Bullock – The Blind
Best Supporting Actor – Christoph Waltz (Inglourious Basterds)
Best Supporting Actress – Penelope Cruz (Nine)
Best Original Screenplay – Mark Boal (The Hurt Locker)
Best Adapted Screenplay – Precious
Best Foreign language Film – The Secret in Their Eyes (El Secreto de Sus Ojos) (Argentina)
Best Original Song – “The Weary Kind” (Crazy Heart) – Ryan Bingham and T-Bone Burnett
Best Original Music Score – Disney/Pixar’s Up
Best Film Editing – The Hurt Locker
Best Sound Editing – The Hurt Locker
Best Sound Mixing – The Hurt Locker
Best Feature Documentary Film – The Cove
Best Short Documentary Film – Music by Prudence
Best Animated Feature Film – Up
Best Animated Short Film – Logorama
Best Live Action Short Film – The New Tenants
Best Cinematography – Avatar
Best Visual Effects – Avatar
Best Art Direction – Avatar
Best Makeup – Star Trek
Best Costume Design – The Young Victoria